Effects of novel 5-HT3 antagonist, N3389, on increased abdominal afferent vagal nerve activities induced by emetic drugs in ferrets.
نویسندگان
چکیده
منابع مشابه
Glucose increases synaptic transmission from vagal afferent central nerve terminals via modulation of 5-HT3 receptors.
Acute hyperglycemia has profound effects on vagally mediated gastrointestinal functions. We have reported recently that the release of glutamate from the central terminals of vagal afferent neurons is correlated directly with the extracellular glucose concentration. The present study was designed to test the hypothesis that 5-HT(3) receptors present on vagal afferent nerve terminals are involve...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1994
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)50217-7